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Multiple Choice

A prescription for Cream XYABA 50 mg/mL is to be dispensed in an actuator pump delivering 0.25 mL per actuation. If directions are to apply 50 mg once daily for 30 days, how many milliliters should be dispensed and how many pumps per day?

Start by converting the daily dose to volume using the cream’s concentration. With 50 mg per 1 mL, delivering 50 mg each day requires 50 mg ÷ (12.5 mg per actuation) = 4 actuations daily. Each actuation is 0.25 mL, so daily volume is 4 × 0.25 mL = 1.0 mL per day. Over 30 days, you need 30 days × 1.0 mL/day = 30 mL total to dispense. Therefore, the prescription should dispense 30 mL in total, and use 4 pumps per day to deliver 1 mL daily (4 pumps × 0.25 mL). Options that show a total of 7.5 mL or 60 mL don’t match the required 30 mL over 30 days, and a daily dose of 2 pumps would only supply 0.5 mL per day (25 mg/day), which is insufficient given the 50 mg/day prescription.

Start by converting the daily dose to volume using the cream’s concentration. With 50 mg per 1 mL, delivering 50 mg each day requires 50 mg ÷ (12.5 mg per actuation) = 4 actuations daily. Each actuation is 0.25 mL, so daily volume is 4 × 0.25 mL = 1.0 mL per day. Over 30 days, you need 30 days × 1.0 mL/day = 30 mL total to dispense. Therefore, the prescription should dispense 30 mL in total, and use 4 pumps per day to deliver 1 mL daily (4 pumps × 0.25 mL).

Options that show a total of 7.5 mL or 60 mL don’t match the required 30 mL over 30 days, and a daily dose of 2 pumps would only supply 0.5 mL per day (25 mg/day), which is insufficient given the 50 mg/day prescription.