Which of the following should be worn for hazardous nonsterile compounding?

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Protecting the eyes and face is the primary safeguard when handling hazardous substances in nonsterile compounding. If there’s any risk of splashes or aerosols, wearing eye protection (goggles or safety glasses) and face protection (face shield) shields the mucous membranes from exposure and is essential. While a chemo-resistant gown is important in specific situations involving hazardous drugs like chemotherapy agents, it isn’t universally required for all hazardous nonsterile compounding scenarios. The other options either don’t provide adequate barrier protection for potential exposure (a cloth laundered gown) or aren’t standard practice for general exposure risk (two pairs of shoe covers). So, eye and face protection whenever exposure risk exists is the most appropriate precaution.